Endocrine Abstracts

Primary hyperparathyroidism (pHPT) resulting from parathyroid tumours is a common endocrine disorder with incompletely understood etiology. In renal failure, secondary hyperparathyroidism (sHPT) occurs with multiple tumour development as a result of calcium and vitamin D regulatory disturbance.The aim of the study was to investigate whether HIC1 may act as a tumour suppressor in the parathyroid glands and whether deregulated expression involves epigeneti...